Your dog was diagnosed with Digital / Subungual Melanoma. All nail bed melanomas should be considered biologically malignant regardless of histological features. Black-coated breeds may be predisposed. Metastatic rate is intermediate between cutaneous and oral melanoma. Compare 2 treatment options for dogs including Digit Amputation, Digit Amputation + Oncept Vaccine — with survival times, costs, and what to expect during treatment.
Pet Cancer Options — Digital / Subungual Melanoma
Canine Oncology Treatment Guide
Digital / Subungual Melanoma
Melanocytic
About This Cancer
Digital melanoma arises from melanocytes in the nail bed or digit and should always be considered biologically malignant, regardless of how benign it may appear under the microscope. This is an important distinction from cutaneous melanoma of the haired skin, where most tumours are benign. The tumour typically presents as swelling of a single toe, often with loss or deformity of the nail, and may initially be mistaken for an infection or nail injury. X-rays often reveal destruction of the bone within the affected toe. The metastatic rate is intermediate between cutaneous and oral melanoma — meaningful but not as high as the oral form. Treatment involves amputation of the affected digit, which dogs tolerate very well functionally. Dark-coated breeds including Rottweilers, Labrador Retrievers, and Schnauzers appear to be at higher risk.
Modified WHO staging
No specific staging system for digital melanoma. Staging follows general melanoma WHO staging adapted for this location. Prognosis driven by presence/absence of metastasis at diagnosis.
Prognostic Factors(2)
Minimum Workup(5 steps)
Median Survival Time Comparison
How long the average patient survives with each treatment
Each treatment is rated by how much published research supports its use. Solid bars indicate stronger evidence; dashed bars mean less certainty.
Please note: All treatment data is sourced from published peer-reviewed literature. Survival times and cost figures are approximate guides. Your pet's individual factors — including tumour grade, stage, and overall health — will influence outcomes and should guide all treatment decisions. The strength-of-evidence rating reflects how much research exists, not how strongly a treatment is recommended. This tool is designed to help you have informed conversations with your veterinary oncologist, not to replace them. Costs shown are US referral centre estimates and may vary significantly by region.